{"id":1140,"date":"2026-03-06T17:35:35","date_gmt":"2026-03-06T16:35:35","guid":{"rendered":"https:\/\/animalwelfare.iph-multisite.berta-bewegt.ch\/?page_id=1140"},"modified":"2026-03-09T14:40:25","modified_gmt":"2026-03-09T13:40:25","slug":"1-introduction-2","status":"publish","type":"page","link":"https:\/\/animalwelfare.interpharma.ch\/fr\/sujets\/grundlagen\/transposition-des-resultats-d-etudes-animales-a-l-homme\/1-introduction-2\/","title":{"rendered":"1. Introduction"},"content":{"rendered":"\n

1. Introduction<\/h2>\n\n\n\n

Sur le long chemin qui m\u00e8ne \u00e0 un m\u00e9dicament, la recherche pharmaceutique a recours \u00e0 l\u2019exp\u00e9rimentation animale \u00e0 la phase pr\u00e9clinique. De nombreuses ann\u00e9es s\u2019\u00e9coulent en g\u00e9n\u00e9ral d\u00e9j\u00e0 avant d\u2019en arriver l\u00e0. Le plus souvent, les chercheuses et chercheurs testent des centaines de milliers de substances pour en trouver une qui pr\u00e9sente le potentiel de freiner ou influencer dans le bon sens l\u2019\u00e9volution d\u2019une maladie. Les premi\u00e8res exp\u00e9riences de cette exp\u00e9dition \u00e0 la d\u00e9couverte de nouvelles substances actives se font dans des solutions et sur des cultures cellulaires. Les exp\u00e9riences sur animaux ne suivent que si certaines conditions sont remplies. L\u2019exp\u00e9rimentation animale sert \u00e0 d\u00e9terminer comment la substance candidate est m\u00e9tabolis\u00e9e dans l\u2019organisme et si elle g\u00e9n\u00e8re des effets n\u00e9fastes. Ce n\u2019est qu\u2019une fois qu\u2019une substance a pass\u00e9 avec succ\u00e8s toutes les exp\u00e9riences pr\u00e9cliniques obligatoires, c\u2019est-\u00e0-dire qu\u2019elle s\u2019est av\u00e9r\u00e9e efficace et inoffensive dans les cultures cellulaires et dans l\u2019organisme animal, que l\u2019on a le droit de la tester chez l\u2019\u00eatre humain dans le cadre d\u2019essais cliniques. Pourquoi tant d\u2019\u00e9tapes pr\u00e9liminaires ?<\/p>\n","protected":false},"excerpt":{"rendered":"

1. Introduction Sur le long chemin qui m\u00e8ne \u00e0 un m\u00e9dicament, la recherche pharmaceutique a recours \u00e0 l\u2019exp\u00e9rimentation animale \u00e0 la phase pr\u00e9clinique. De nombreuses ann\u00e9es s\u2019\u00e9coulent en g\u00e9n\u00e9ral d\u00e9j\u00e0 avant d\u2019en arriver l\u00e0. Le plus souvent, les chercheuses et chercheurs testent des centaines de milliers de substances pour en trouver une qui pr\u00e9sente le […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1146,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/unterthema.php","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-1140","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\n1. Introduction - animalwelfare<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/animalwelfare.interpharma.ch\/fr\/sujets\/grundlagen\/transposition-des-resultats-d-etudes-animales-a-l-homme\/1-introduction-2\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"1. Introduction\" \/>\n<meta property=\"og:description\" content=\"1. Introduction Sur le long chemin qui m\u00e8ne \u00e0 un m\u00e9dicament, la recherche pharmaceutique a recours \u00e0 l\u2019exp\u00e9rimentation animale \u00e0 la phase pr\u00e9clinique. De nombreuses ann\u00e9es s\u2019\u00e9coulent en g\u00e9n\u00e9ral d\u00e9j\u00e0 avant d\u2019en arriver l\u00e0. 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