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Report 2023

Institute of Human Biology
Reducing the number of animals by introducing a new method for better evaluating the dynamics of metastatic burden in vivo
Replacing animals by imitating the interactions between synoviocytes and endothelial cells in vitro
Reducing animal numbers by using a novel device
Biomedical Research Awareness Day (BRAD)
Reducing stress in study animals
Introduction of a fourth “R prize” for the category of “Responsibility”
National promotion of the 3Rs by the 3RCC
“Innovation in the 3Rs” programme
The Global Animal Technician Recognition Day celebrates the heroes of animal care
Animal Welfare 4R Day
Creating a Culture of Care
Refinement in vivarium
Project Capricorn
Non-aversive handling
In-house training

Reducing animal numbers by using a novel device

In this study, a novel device for the topical application of medication to the eye was developed with the aim of simplifying accurate dosing, supporting the application of treatments to the eye, and increasing patient comfort while the treatment is being applied. This approach led to a design and analysis that allowed the total number of animals to be reduced tenfold.

Project name: Using sound statistical principles
Charter articles: 1, 2

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