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Report 2023

Institute of Human Biology
Reducing the number of animals by introducing a new method for better evaluating the dynamics of metastatic burden in vivo
Replacing animals by imitating the interactions between synoviocytes and endothelial cells in vitro
Reducing animal numbers by using a novel device
Biomedical Research Awareness Day (BRAD)
Reducing stress in study animals
Introduction of a fourth “R prize” for the category of “Responsibility”
National promotion of the 3Rs by the 3RCC
“Innovation in the 3Rs” programme
The Global Animal Technician Recognition Day celebrates the heroes of animal care
Animal Welfare 4R Day
Creating a Culture of Care
Refinement in vivarium
Project Capricorn
Non-aversive handling
In-house training

“Innovation in the 3Rs” programme

One member company has set up an “Innovation in the 3Rs” programme. The aim of this programme is to inspire and support the member company’s scientists in rethinking the way they conduct their research by providing them with the resources they need to develop and validate new ways of replacing, reducing and refining animal experiments. The “Innovation in the 3Rs” programme selects and supports novel research projects that would otherwise be unlikely to come to fruition. In 2022, five reduction and refinement projects were supported. The projects supported in 2022 have highlighted new ways in which the member company can reduce the number of animals needed for discovering and developing drugs by means of organs-on-a-chip, artificial intelligence (AI) and organoids, and how it can improve the experiences of the animals being studied by using digital home cages and delayed-release analgesics.

Project name: Innovation in the 3Rs
Charter articles: 1, 2, 3

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